Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists
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![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://europepmc.org/articles/PMC6556150/bin/nihms-1029202-f0009.jpg)
Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts. - Abstract - Europe PMC
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://pubs.acs.org/cms/10.1021/jacs.8b11309/asset/images/large/ja-2018-113095_0009.jpeg)
One-Pot 1,1-Dihydrofluoroalkylation of Amines Using Sulfuryl Fluoride
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://pubs.acs.org/cms/10.1021/jacs.8b11309/asset/images/medium/ja-2018-113095_0003.gif)
One-Pot 1,1-Dihydrofluoroalkylation of Amines Using Sulfuryl Fluoride
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://html.scirp.org/file/1-2501061x2.png)
Directing the Metabolism of Drugs Away from CYP450: The Use of Oxetane Rings
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://ars.els-cdn.com/content/image/1-s2.0-S0969996119303055-ga1.jpg)
CXCR2 antagonism promotes oligodendrocyte precursor cell differentiation and enhances remyelination in a mouse model of multiple sclerosis - ScienceDirect
Highly enantioselective borane reduction of ketones catalyzed by chiral oxazaborolidines. Mechanism and synthetic implications
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://ars.els-cdn.com/content/image/1-s2.0-S0969996119303055-gr4.jpg)
CXCR2 antagonism promotes oligodendrocyte precursor cell differentiation and enhances remyelination in a mouse model of multiple sclerosis - ScienceDirect
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://pubs.acs.org/cms/10.1021/acs.jmedchem.3c00630/asset/images/medium/jm3c00630_0001.gif)
Discovery of CVN417, a Novel Brain-Penetrant α6-Containing Nicotinic Receptor Antagonist for the Modulation of Motor Dysfunction
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://pubs.acs.org/cms/10.1021/acs.orglett.2c01827/asset/images/large/ol2c01827_0003.jpeg)
Chan–Lam Reaction and Lewis Acid Promoted 1,3-Rearrangement of N–O Bonds to Prepare N-(2-Hydroxyaryl)pyridin-2-ones
Chan–Lam Reaction and Lewis Acid Promoted 1,3-Rearrangement of N–O Bonds to Prepare N-(2-Hydroxyaryl)pyridin-2-ones
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://europepmc.org/articles/PMC6556150/bin/nihms-1029202-f0012.jpg)
Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts. - Abstract - Europe PMC
![Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists](https://pubs.acs.org/cms/10.1021/acs.jmedchem.7b01854/asset/images/medium/jm-2017-01854x_0014.gif)
Discovery of Novel 1-Cyclopentenyl-3-phenylureas as Selective, Brain Penetrant, and Orally Bioavailable CXCR2 Antagonists
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